![]() This drug it takes about 4 days to get the full effect. When you take the next 10mg dose 24 hours later, you still have roughly half of yesterdays dose in your blood, so adding 10mg to it is going to have the effect of 15mg, from half of yesterday dose still being around. You take todays dose and it puts 10mg worth of drug into your bloodstream. ![]() Lets say youre on 10mg of a drug with a 24 hour half life. This is from the long half life (not the effective duration, thats different) basically how fast or slow your body eliminates a drug. ![]() It takes about 4 days for these buprenorphine based drugs to get up to full speed in your body. Oh, also, for the 1st 3 days I took the Belbuca I had horrible headaches but they went away. A few months ago I had to move and I was in terrible pain but I had to get my things out by the next day so I took a 450 belbuca every 4 hours, it didn't seem to offer any more help after 3 doses, Made me a bit dizzy and affected my vision though. My doc added Tramadol 50mg 2xday but that doesn't really seem to make a difference. I usually take my second 12 hour dose a few hours early so I can take care of the house in the evening since I will be sleeping through the early hour withdrawals. It also does help my mood a bit, I start to notice a slight withdrawal at about 6-8 hours. It doesn't take away all my pain (4 herniated, 3 bulging disc's in cervical and lumbar) but it allows me to work. I started at 300 and it was definitely better than the Butrans! After a car accident my dose is up to 450. Finally Igot a new pain doc and she switched me to Belbuca. ![]() The patch was supposed to last for 7 days but it didn't stay on my skin without really strong bandages and the slight relief wore off after about 4 days. I went up to the highest dose within 6 months but I had to cut back on work because the pain was still there. My doc said I would not notice a difference and started me on the lowest dose.I was not warned about the crippling withdrawal symptoms. When they switched me from norco to butrans as a wonderful surprise at my monthly visit it was horrible. ![]()
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